Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management.
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Authors
Heringa, Minne BCnubben, Nicole H P
Slob, Wout
Pronk, Marja E J
Muller, Andre
Woutersen, Marjolijn
Hakkert, Betty C
Type
ArticleLanguage
en
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Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management.Published in
Regul Toxicol Pharmacol 2020; 114:104659PMID
32334038ae974a485f413a2113503eed53cd6c53
10.1016/j.yrtph.2020.104659
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