• Air pollution and airway resistance at age 8 years - the PIAMA birth cohort study.

      Finke, Isabelle; de Jongste, Johan C; Smit, Henriette A; Wijga, Alet H; Koppelman, Gerard H; Vonk, Judith; Brunekreef, Bert; Gehring, Ulrike (2018-07-17)
      Air pollution has been found to adversely affect children's lung function. Forced expiratory volume in 1 s and forced vital capacity from spirometry have been studied most frequently, but measurements of airway resistance may provide additional information. We assessed associations of long-term air pollution exposure with airway resistance.
    • A comparison of associations with childhood lung function between air pollution exposure assessment methods with and without accounting for time-activity patterns.

      Ntarladima, Anna-Maria; Karssenberg, Derek; Vaartjes, Ilonca; Grobbee, Diederick E; Schmitz, Oliver; Lu, Meng; Boer, Jolanda; Koppelman, Gerard; Vonk, Judith; Vermeulen, Roel; et al. (2021-07-16)
      We compared four annual average air pollution exposure assessment methodologies; two rely on residential exposures only, the other two incorporate estimated time activity patterns. The time-activity patterns were based on assumptions about the activity space and make use of available external data sources for the duration of each activity. Mapping of multiple air pollutants (NO2, NOX, PM2.5, PM2.5absorbance, PM10) at a fine resolution as input to exposure assessment was based on land use regression modelling. First, we assessed the correlations between the exposures from the four exposure methods. Second, we compared estimates of the cross-sectional associations between air pollution exposures and lung function at age 8 within the PIAMA birth cohort study for the four exposure assessment methodologies.