• The role of aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and hypertension risk: results of a pooled analysis from seven European countries.

      Baudin, Clémence; LefÈvre, Marie; Babisch, Wolfgang; Cadum, Ennio; Champelovier, Patricia; Dimakopoulou, Konstantina; Houthuijs, Danny; Lambert, Jacques; Laumon, Bernard; Pershagen, Göran; et al. (2020-09-10)
    • The role of aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use: results of a pooled-analysis from seven European countries.

      Baudin, Clémence; Lefèvre, Marie; Babisch, Wolfgang; Cadum, Ennio; Champelovier, Patricia; Dimakopoulou, Konstantina; Houthuijs, Danny; Lambert, Jacques; Laumon, Bernard; Pershagen, Göran; et al. (2021-02-05)
      A significant association was found between aircraft noise levels at night and antihypertensive medication only in the UK (OR = 1.43, 95%CI 1.19-1.73 for a 10 dB(A)-increase in Lnight). No association was found with other medications. Aircraft noise annoyance was significantly associated with the use of antihypertensive medication (OR = 1.33, 95%CI 1.14-1.56), anxiolytics (OR = 1.48, 95%CI 1.08-2.05), hypnotics and sedatives (OR = 1.60, 95%CI 1.07-2.39), and antasthmatics (OR = 1.44, 95%CI 1.07-1.96), with no difference between countries. Noise sensitivity was significantly associated with almost all medications, with the exception of the use of antasthmatics, showing an increase in ORs with the level of noise sensitivity, with differences in ORs among countries only for the use of antihypertensive medication. The results also suggested a mediating role of aircraft noise annoyance and a modifying role of both aircraft noise annoyance and noise sensitivity in the association between aircraft noise levels and medication use.
    • Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries.

      Baudin, Clémence; Lefèvre, Marie; Selander, Jenny; Babisch, Wolfgang; Cadum, Ennio; Carlier, Marie-Christine; Champelovier, Patricia; Dimakopoulou, Konstantina; Huithuijs, Danny; Lambert, Jacques; et al. (2019-11-27)
      Statistically significant increases of evening cortisol levels were shown in women with a 10-dB(A) increase in aircraft noise exposure in terms of LAeq, 16h (exp(β) = 1.08; CI95% = 1.00-1.16), Lden (exp(β) = 1.09; CI95% = 1.01-1.18), Lnight (exp(β) = 1.11; CI95% = 1.02-1.20). A statistically significant association was also found in women between a 10-dB(A) increase in terms of Lnight and the absolute variation per hour (exp(β) = 0.90; CI95% = 0.80-1.00). Statistically significant decreases in relative variation per hour were also evidenced in women, with stronger effects with the Lnight (exp(β) = 0.89; CI95% = 0.83-0.96) than with other noise indicators. The morning cortisol levels were unchanged whatever noise exposure indicator considered. There was no statistically significant association between aircraft noise exposure and cortisol outcomes in men.